What to Expect in Your First 30 Days on Semaglutide

Slim woman in oversized jeans from weight loss with Semaglutide in Livermore, CAIs weight loss on your list of New Year’s resolutions for 2026? Starting Semaglutide is an exciting step toward achieving long-term weight loss, but many patients wonder what the first month will look like. Here’s what to expect initially.

At Lūx MD, patients beginning their Semaglutide journey benefit from a luxurious, medically guided wellness experience led by board-certified physician Dr. Christine Rongey, whose expertise ensures every treatment plan is personalized and rooted in advanced medical science.

Week 1: Getting Started and Adjusting

Most patients begin Semaglutide at a low dose to help the body adjust gradually. During the first week, you may notice decreased appetite, feeling full sooner, or reduced cravings, some of the earliest signs that the medication is working. Mild side effects include nausea, fatigue, or minor digestive changes, but these are typically manageable. Eating smaller meals, staying hydrated, and avoiding heavy or greasy foods can minimize discomfort.

Week 2: Appetite Changes and Early Wins

By the second week, appetite suppression becomes more noticeable. Many patients find it easier to stick to healthier eating habits simply because they’re not as hungry as they used to be. You may see the scale begin to shift, but remember that results vary. Some individuals experience increased energy as their bodies adjust, while others may still have mild side effects.

Week 3: Establishing a Routine

Around week three, your body becomes more accustomed to the medication, and side effects tend to lessen. This is a great time to focus on supportive lifestyle habits: balanced meals, regular movement, and mindful eating. Semaglutide works best when paired with consistent, healthy routines.

Week 4: Visible Progress and Long-Term Focus

By the end of the first 30 days, many patients notice meaningful changes in appetite, eating behaviors, and sometimes even weight. While you shouldn’t expect dramatic results this early, most people feel more in control of their cravings and more optimistic about their long-term progress. Your provider may assess your response and determine whether a dosage adjustment is appropriate.

Achieve Lasting Weight Loss with Semaglutide and Support in Livermore, CA

The first month on Semaglutide is a process of adaptation, small victories, and building habits that set the stage for lasting success. Call us today at 925-292-9203 to schedule an appointment.

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